SYNTHESIS OF (S)-(-ALPHA-METHOXYMETHYLDIHYDRO-COUMARIN - ABSOLUTE-CONFIGURATION OF THE REDUCED PRODUCT IN ENANTIOSELECTIVE RADICAL-MEDIATEDREDUCTION())

Authors
MURAKATA M TSUTSUI H HOSHINO O
Citation
M. Murakata et al., SYNTHESIS OF (S)-(-ALPHA-METHOXYMETHYLDIHYDRO-COUMARIN - ABSOLUTE-CONFIGURATION OF THE REDUCED PRODUCT IN ENANTIOSELECTIVE RADICAL-MEDIATEDREDUCTION()), Heterocycles, 46, 1997, pp. 517-522
Citations number
9
Journal title
Heterocycles → ACNP
ISSN journal
03855414
Volume
46
Year of publication
1997
Pages
517 - 522
Database
ISI
SICI code
0385-5414(1997)46:<517:SO(-A>2.0.ZU;2-F
Abstract
(S)-(+)-alpha-Methoxymethyldihydrocoumarin was synthesized starting fr om (R)-2-benzyl-3-hydroxypropyl acetate. Consequently, the absolute co nfiguration of the reduced product obtained by radical-mediated reduct ion of alpha-iodo-alpha-methoxymethyldihydrocoumarin was determined to be R.