CAN COMBINED T-CELL-BASED AND ANTIBODY-BASED IMMUNOTHERAPY OUTSMART TUMOR-CELLS

Authors
ABKEN H HOMBACH A REINHOLD U FERRONE S
Citation
H. Abken et al., CAN COMBINED T-CELL-BASED AND ANTIBODY-BASED IMMUNOTHERAPY OUTSMART TUMOR-CELLS, Immunology today, 19(1), 1998, pp. 2-5
Citations number
24
Categorie Soggetti
Immunology
Journal title
Immunology today → ACNP
ISSN journal
01675699
Volume
19
Issue
1
Year of publication
1998
Pages
2 - 5
Database
ISI
SICI code
0167-5699(1998)19:1<2:CCTAAI>2.0.ZU;2-R
Abstract
Advantages of T-cell- and antibody-based immunotherapy can be combined by grafting cytotoxic T lymphocytes with chimeric receptors composed of antibody fragments (which recognize tumor-cell antigen) and a cellu lar activation motif. Here, Hinrich Abken and colleagues discuss the p otential of this approach for immunotherapy of malignant diseases.