HYPERINTENSE SUBCORTICAL BRAIN ALTERATIONS IN ANOREXIA-NERVOSA

Objective: The results of past research have identified changes in bra in structure in anorexia nervosa. We observed previously unreported MR I alterations in two cases of anorexia nervosa. Method: For both cases , we reviewed the clinical history, MRI scans and conducted a pertinen t literature review. Results: The MRI brain scans of two patients with the diagnosis of anorexia nervosa revealed evidence of subcortical hy perintense changes on T2-weighted images. Discussion: No previous repo rts of these findings have been described in the literature on anorexi a nervosa to date. Clinical and pathologic correlates associated with these brain observations in anorexia nervosa are discussed. (C) 1997 b y John Wiley & Sons, Inc.