Bj. Losson et al., FIELD EFFICACY OF INJECTABLE DORAMECTIN AGAINST CHORIOPTES BOVIS IN NATURALLY INFECTED CATTLE, Veterinary record, 142(1), 1998, pp. 18-19
A single subcutaneous injection of doramectin at a dose rate of 200 mu
g/kg bodyweight was effective in controlling an infection of Choriopt
es bovis mites in naturally infected cattle, From 14 days after treatm
ent, the geometric mean number of live mites was significantly lower (
P<0.001) in the doramectin-treated cattle than in the control group at
each sampling until day 35, The percentage efficacy (treated versus c
ontrols) of doramectin against C bovis at day 35 was 99.9 per cent and
the percentage reduction (day 35 versus day 0) in the treated animals
was 99.3 per cent, At day 35, all seven controls were still positive
for C bovis whereas five of the eight doramectin-treated animals were
free of live mites.