Yh. Ho et al., MARSUPIALIZATION OF FISTULOTOMY WOUNDS IMPROVES HEALING - A RANDOMIZED CONTROLLED TRIAL, British Journal of Surgery, 85(1), 1998, pp. 105-107
Background Marsupialization of anal fistulotomy wounds leaves less raw
unepithelialized tissue to granulate and may improve wound healing. M
ethods Some 103 consecutive patients with uncomplicated intersphincter
ic or trans-sphincteric fistula in ano were recruited into a randomize
d controlled trial. Fistula tracts were identified and laid open under
general anaesthesia. The patients were randomized to have either the
wounds left open (LO group) or wound edges marsupialized to the fistul
a tract with interrupted absorbable sutures (MS group). Anal manometry
was performed before operation, and 6 weeks and 3 months after surger
y. Results Some 52 patients were randomized to the LO group and 51 to
the MS group. There were no differences in the age, sex, fistula type
and fistula length distribution between the groups. Mean follow-up tim
es were 9 and 10.2 months respectively. Wounds in the MS group healed
faster (mean (s.e.m.) 6.0 (0.4) weeks) than those in the LO group (10.
0 (0.5) weeks) (P < 0.001). Only one patient (2 per cent) in the MS gr
oup was incontinent of liquids after operation compared with six (12 p
er cent) in the LO group. There was less impairment in maximum anal sq
ueeze pressure at 3 months after marsupialization compared with leavin
g fistulotomy wounds open (P < 0.05). Apart from a slightly longer ope
rative time required for marsupialization, the hospitalization and com
plication rates were the same. Conclusion Anal fistulotomy wounds heal
ed faster after marsupialization. Anal squeeze pressures were better p
reserved and this may improve anal continence.