T. Watanabe et al., SUCCESSFUL MANAGEMENT OF PREGNANCY IN A PATIENT WITH VON-WILLEBRAND-DISEASE-NORMANDY, Obstetrics and gynecology, 89(5), 1997, pp. 859-859
Von Willebrand disease Normandy, a rare variant of von Willebrand dise
ase, was first reported in 1989.(1) Its clinical features resemble tho
se of hemophilia A and are caused by a low level of factor WI coagulan
t activity, which results from the defective binding of von Willebrand
factor to factor VIII.(2) Profuse postpartum bleeding is expected if
no treatment is given.(3) There are no previous reports on the managem
ent of pregnant patients with established von Willebrand disease Norma
ndy.