J. Behnke et al., INTRAAXIAL ENDOPHYTIC TUMORS IN THE PONS AND OR MEDULLA-OBLONGATA .1.SYMPTOMS, NEURORADIOLOGICAL FINDINGS, AND HISTOPATHOLOGY IN 30 CHILDREN/, Child's nervous system, 13(3), 1997, pp. 122-134
Between August 1987 and June 1994 we operated upon 30 consecutive chil
dren suffering from endophytic intra-axial tumors located in the pens
and/or medulla oblongata. We present the clinical findings, neuroradio
logical aspects and histopathological results recorded in these cases.
Diagnostic tests included clinical examinations, neurophysiological t
ests and neuroradiological imaging [magnetic resonance tomography (MRT
) in all cases, often combined with cranial computer tomography (CCT)]
. The diagnosis was confirmed by histopathological examination of the
tumor material obtained by open surgical exploration in all cases. We
conclude that a short history and more horizontal growth within the pe
ns are more valuable predictors of the histopathology than differentia
tion between focal or diffuse growth patterns. MRT has little predicti
ve value for histopathological diagnosis in intra-axial brain stern tu
mors.