MULTIPLE INTRACRANIAL MIXED GERM-CELL TUMORS

A case of sequential occurrence of multiple intracranial mixed germ ce ll tumors is presented. An 8-year-old boy with a cystic calcified tumo r in the basal ganglia and an increased serum alpha-fetoprotein concen tration was initially treated with radiotherapy. Six years later, a tu mor composed of embryonal carcinoma and immature teratoma arose from t he right temporo-parietal lobe. This tumor was treated successfully wi th surgery and radiochemotherapy, The possibility of multicentricity o r intra-axial metastasis distant from the original site during the lon g-term course should be considered in treatment for intracranial germ cell tumors.