SEVERE NEUROLOGICAL COMPLICATIONS IN ASSOCIATION WITH EPSTEIN-BARR-VIRUS INFECTION

Involvement of the nervous system in infectious mononucleosis is commo n. About 50% have headache an presentation, Neck stiffness without men ingitis is a frequent finding. Severe neurological complications are r are though, occurring in fewer than 0.5%. We describe two patients wit h unusual and severe neurological complications in association with se rological evidence of EBV-infection: a 32-year old female developed a bilateral optic neuritis combined with a transverse myelitis and a 72- year old man developed mononeuritis multiplex, autonomic neuropathy an d a salt-wasting nephropathy.