Vd. Dyachenko et al., SYNTHESIS AND SOME PROPERTIES OF L-5-CYANO-6-MERCAPTO-3,4-DIHYDROPYRIDIN-2(1H)-ONES, Russian chemical bulletin, 46(11), 1997, pp. 1912-1915
Condensation of propionic (or acetic) aldehyde, cyanothioacetamide, Me
ldrum's acid, and N-methylmorpholine occurs via the intermediate forma
tion of the corresponding Michael adducts and yields 5-cyano-6-mercapt
o-3,4-dihydropyridin-2-(1H)-ones. The oxidation of the reaction produc
ts with DMSO and their alkylation were studied.