Extensive research indicates a strong relationship between endogenous
opioid peptides (EOPs) and food intake. In the present paper, we propo
se that food cravings act as an intervening variable in this opioid-in
gestion link. Specifically, we argue that altered EOP activity may eli
cit food cravings which in turn may influence food consumption. Correl
ational support for this opioidergic theory of food cravings is provid
ed by examining various clinical conditions (e.g. pregnancy, menstruat
ion, bulimia, stress, depression) which are associated with altered EO
P levels, intensified food cravings, and increased food intake. (C) 19
97 Academic Press Limited.