SYNTHESIS OF SOME NEW 2-(PYRAZOL-1-YL)-4-(PYRIMIDIN-5-YL)THIAZOLES

Citation
Vk. Ahluwalia et al., SYNTHESIS OF SOME NEW 2-(PYRAZOL-1-YL)-4-(PYRIMIDIN-5-YL)THIAZOLES, Indian journal of chemistry. Sect. B: organic chemistry, including medical chemistry, 36(10), 1997, pp. 920-922
Citations number
7
Categorie Soggetti
Chemistry Inorganic & Nuclear
ISSN journal
03764699
Volume
36
Issue
10
Year of publication
1997
Pages
920 - 922
Database
ISI
SICI code
0376-4699(1997)36:10<920:SOSN2>2.0.ZU;2-J
Abstract
The reaction of 1, hloroacetyl-4,6-dioxo-2-thioxohexahydropyrimidines 2a-h with thiosemicarbazide gives 2-hydrazino-4-[1, 3-diaryl-4, 6-diox o-2-thioxohexahydropyrimidin-5-yl]thiazoles 3a-h, which on condensatio n with acetyl acetone yield 4-[1, 3-diaryl-4, 6-dioxo-2-thioxohexahydr opyrimidin-5-yl]-2-[3, 5-dimethyl-1 H-pyrazol-1-yl]thiazoles 4a-h.