S. Celayir et al., A MODIFIED MITROFANOFF PROCEDURE USING THE RECTUS-ABDOMINIS MUSCLE FLAP TECHNIQUE - A PRELIMINARY-REPORT IN A RABBIT MODEL, British Journal of Urology, 81(1), 1998, pp. 83-86
Objective To create a modified Mitrofanoff continent stoma in a rabbit
model, using a rectus abdominis muscle flap (RAMF) with its intact va
scular supply. Materials and methods Fifteen New Zealand White male ra
bbits underwent an operation to create a 6 cm long tube using a RAMF w
ith its vascular pedicle from the inferior epigastric vessels, The int
ernal orifice of the tube was anastomosed to the anterior bladder wall
with 5/0 polyglactin sutures. The external orifice was directly sutur
ed to the skin to fashion a catheterizable Mitrofanoff stoma, A 6 F ca
theter was left in the tube as a stent for 2 weeks, Radiography and hi
stopathological investigations were carried out for 8 weeks after surg
ery. Results Intravenous pyelography and voiding cystourethrography sh
owed a normal looking urinary system; contrast studies showed an intac
t RAMF tube with no signs of stricture. Catheterization of the stoma w
as possible in each animal, Histopathologically, there was no evidence
of severe fibrosis or inflammatory changes: the inner surface of the
tube (proximal bladder side) was covered by transitional urinary epith
elium in most of the animals, Conclusion It is possible to create a Mi
trofanoff tube using a vascularized RAMF in a rabbit model, Using this
technique there is no need to perform a major operation in the gastro
intestinal system. The technique may provide a good alternative treatm
ent in those patients who need a combination of Mitrofanoff and antegr
ade continence enema surgery, and in patients with previous appendecto
my.