CORRELATION OF MIDDLE LATENCY AUDITORY-EVOKED POTENTIALS AND CEREBRALBLOOD-FLOW CHANGES

The purpose of this study is to find the correlation between middle la tency auditory evoked potentials (MLAEP) and sound activated single ph oton emission computed tomography (SPECT) studies. This study was perf ormed on six normal right-handed volunteers with a mean age of 35.2 +/ - 7.6 years, using the split-dose technique. First, a SPECT study was performed on subjects in blinded, awake and silent states. After bilat eral ears were stimulated with a click sound, MLAEP and a second SPECT study were performed. Subtraction of the first SPECT from the second SPECT revealed a statistically significant increase of cerebral blood flow (CBF) in the bilateral superior temporal region. Bilateral Na amp litudes of MLAEP had a statistically significant and good correlation with the percentages of CBF changes in the bilateral superior temporal region. The superior temporal cerebral blood now activation can be ex pressed by electrophysiological activation. Moreover, correlation duri ng the left Na components and left frontal and occipital lobe are disc ussed.