A SAFETY STUDY OF THALLIUM-CONTAINING CERAMIC SUPERCONDUCTOR MATERIALIN RATS

Citation
Jp. Mulkey et Fw. Oehme, A SAFETY STUDY OF THALLIUM-CONTAINING CERAMIC SUPERCONDUCTOR MATERIALIN RATS, Veterinary and human toxicology, 40(1), 1998, pp. 11-14
Citations number
22
Categorie Soggetti
Toxicology,"Veterinary Sciences
ISSN journal
01456296
Volume
40
Issue
1
Year of publication
1998
Pages
11 - 14
Database
ISI
SICI code
0145-6296(1998)40:1<11:ASSOTC>2.0.ZU;2-M
Abstract
Thallium is a highly toxic cumulative poison in humans and animals. Th e use of the metal as a component in ceramic superconductor material ( CSM) raised concern about the health risk of CSM to children accidenta lly swallowing some of the CSM or to occupationally-exposed workers in the electronics industry. This study examined the biological availabi lity of CSM by quantifying the thallium content in organs, blood and f ecal matter of Sprague-Dawley rats after a single acute oral exposure to CSM and compares these values to similar thallium measurements from identical exposure to thallium sulfate. The CSM-exposed group had sig nificantly less thallium than the thallium sulfate-exposed group in al l tissues/fluids analyzed. This suggested that CSM poses a lower healt h risk to exposed persons than thallium sulfate.