FAMILIAL DISCRETE SUBAORTIC STENOSIS

Discrete subaortic stenosis (DSS) accounts for 8 to 20% of all cases o f congenital left ventricular outflow tract obstruction. There have be en few scattered reports of left ventricular obstructive lesions occur ring in immediate family members of patients with DSS. This is a repor t of four cases of DSS in one family: one brother with a fibrous ring, and two sisters and the son of one of the sisters with a fibrous memb rane. The occurrence of multiple cases of DSS in this family suggests an autosomal dominant mode of inheritance.