This report describes an unusual reaction to injected subconjunctival
corticosteroid. The authors examined a patient with large areas of con
junctival necrosis at the site of a previous subconjunctival corticost
eroid injection. A Gram's stain and culture of the affected conjunctiv
al area and the bottled corticosteroid suspension were negative. Necro
sis of the conjunctiva is a heretofore unreported adverse reaction to
a subconjunctival corticosteroid injection. These lesions probably rep
resent a localized toxic reaction rather than a sequela of infection.
Conjunctival necrosis has been known to occur following various microb
ial infections, chemical burns, and certain topical and subconjunctiva
l antibiotics. We describe an interesting and unusual case of conjunct
ival necrosis following the administration of subconjunctival corticos
teroid.