OBJECTIVE: Because hypoparathyroidism is a serious complication of thy
roidectomy, we attempted to elucidate factors determining the risk of
this postoperative outcome. SETTING:Four tertiary care hospitals in Al
buquerque, New Mexico. PATIENTS: A retrospective study of 142 patients
who underwent total or subtotal thyroidectomy between 1988 and 1995.
MEASUREMENTS ANO MAIN RESULTS: Permanent hypoparathyroidism was define
d as hypocalcemic symptoms plus a requirement for oral vitamin D or ca
lcium 6 months after thyroidectomy. Factors analyzed to determine thei
r contribution to the risk of persistent postoperative hypoparathyroid
ism were the indication for thyroidectomy, performance of a preoperati
ve thyroid needle biopsy, type of surgery, postoperative pathology, pr
esence and stage of thyroid carcinoma, resident surgeon involvement, a
nd specialty of the surgeon performing the procedure. Surgical special
ty and stage of thyroid carcinoma were independent risk factors for pe
rsistent postoperative hypoparathyroidism by multivariate analysis. Ni
ne (29%) of 31 patients who had thyroidectomy by otolaryngologists met
criteria for permanent hypoparathyroidism, and 6 (5%) of 111 patients
who had thyroidectomy by general surgeons met the same criteria (p <
.001), Adjustment for the effect of stage did not eliminate the effect
of specialty (p = .006), and adjustment for the effect of specialty d
id not eliminate the effect of stage [p = .02) on the occurrence of po
stoperative hypoparathyroidism. CONCLUSIONS: We conclude from our data
that patients undergoing thyroidectomy by an otolaryngologist may be
at a higher risk of permanent postoperative hypoparathyroidism than pa
tients who undergo thyroidectomy by a general surgeon. This may reflec
t differences in case selection or surgical approach or both.