Background Little is known about the outcome of common mental disorder
s. (CMD) in primary care attenders in low income countries. Method Two
and 12 month (T1 and T2) follow-up of a cohort of cases of CMD (n=199
) recruited from primary health, traditional medical practitioner, and
general practitioner clinics in Harare, Zimbabwe. The Shona Symptom Q
uestionnaire (SSQ) was the measure of caseness. Results The persistenc
e of case level morbidity was recorded in 41% of subjects at 12 months
. Of the 134 subjects interviewed at both follow-up points, 49% had re
covered by T1 and remained well at T2 while 28% were persistent cases
at both T1 and T2. Higher SSQ scores, a psychological illness model, b
ereavement and disability predicted a poor outcome at both times. Poor
er outcome at TI only was associated with a causal model of witchcraft
and an unhappy childhood. Caseness at follow-up was associated with d
isability and economic deprivation. Conclusions A quarter of cases of
CMD were likely to be ill throughout the 12 month follow-up period. Ta
rgeting risk groups for poor outcome for interventions and policy inte
rventions to reduce the impact of economic deprivation may provide a w
ay of tackling CMD in primary care in low income countries.