Between ir March 1992 and 31 June 1996, we enrolled 72 patients with l
eft ventricular aneurysms in a ?prospective, nonrandomized study to co
mpare-by study of cardiac indices, single-plane ejection fractions, an
d nuclear ventriculograms-the effects of classical aneurysmectomy (gro
up I, n=36) with those of endoaneurysmorrhaphy (group 2, n=36). Preope
rative and postoperative cardiac index measurements were, respectively
, 1.96 +/- 0.6 and 3.51 +/- 0.53 for group I, and 1.96 +/- 0.31 and 3.
43 +/- 0.41 for group 2. in this regard, there was not any significant
difference between the groups preoperatively or postoperatively. Preo
perative and postoperative multiple-gated acquisition measurements wer
e, respectively, 34.3 +/- 7.76 and 43.1 +/- 11.1 for group I, and 37 /- 3.88 and 66.5 +/- 5.2 for group 2. Although there was not any signi
ficant preoperative difference between the groups (P=0.34), group 2 ha
d significant postoperative improvement in left ventricular ejection f
ractions (P<0.001). Preoperative and postoperative single-plane contra
st ventriculographic ejection fractions were, respectively, 43.4 +/- 8
.7 and 48.6 +/- 11.2 for group 1, and 43.8 +/- 5.5 and 60.8 +/- 15.1 f
or group 2. Again, there was not any significant difference between th
e 2 groups in preoperative left ventricular ejection fractions (P=0.87
), but the postoperative left ventricular ejection fractions of group
2 were significantly better than those of group I (P=0.022). We conclu
de that left ventricular functional improvement with endoaneurysmorrha
phy is superior to that with classical aneurysmectomy.