A. Paszkowska et al., SIALIC-ACID CONCENTRATION IN SERUM AND TISSUE OF ENDOMETRIAL CANCER-PATIENTS, European journal of obstetrics, gynecology, and reproductive biology, 76(2), 1998, pp. 211-215
Serum total sialic acid (TSA) level was determined in the group of 45
patients with endometrial neoplasia. Moreover, the sialic acid content
in 23 surgically obtained tumor tissue specimens has been estimated.
The mean value of serum total sialic acid level of the cancer patients
(2.38 mmol/l) was significantly higher (P<0.0001) than the sialic aci
d level in the control group (1.52 mmol/l). The elevation of serum tot
al sialic acid level was associated with the burden of the tumor (2.30
mmol/l and 2.68 mmol/l for stages I and II + III, respectively). Tiss
ue sialic acid content showed no significant differences between early
and advanced clinical stage of the disease. (C) 1998 Published by Els
evier Science Ireland Ltd.