N. Markova et al., INFLUENCE OF BLOOD-TRANSFUSION ON BACTERICIDAL ACTIVITY OF HUMAN-LEUKOCYTES AND SERA AGAINST YERSINIA-ENTEROCOLITICA AND SALMONELLA-TYPHIMURIUM, FEMS immunology and medical microbiology, 19(4), 1997, pp. 261-265
Patients undergoing joint surgery and blood transfusion were studied.
Serum and leukocyte bactericidal tests in vitro against Salmonella typ
himurium and Yersinia enterocolitica were carried out preoperatively a
s well as on the 1st, 3rd and 7th days after the operation. The serum
complement (C3 and C4) concentrations were determined at the same inte
rvals. It was found that after blood transfusion the bactericidic acti
vity of sera and the serum C3 complement concentrations were increased
. In contrast the killing ability of leukocytes was suppressed. (C) 19
98 Federation of European Microbiological Societies. Published by Else
vier Science B.V.