SYNTHESIS OF IMINOPOLYOLS VIA HENRY REACTION - A SHORT ROUTE TO THE ALPHA-MANNOSIDASE INHIBITOR 1,4-DIDEOXY-1,4-IMINO-D-MANNITOL AND TO AMINO ANALOGS

Authors
KIESS FM POGGENDORF P PICASSO S JAGER V
Citation
Fm. Kiess et al., SYNTHESIS OF IMINOPOLYOLS VIA HENRY REACTION - A SHORT ROUTE TO THE ALPHA-MANNOSIDASE INHIBITOR 1,4-DIDEOXY-1,4-IMINO-D-MANNITOL AND TO AMINO ANALOGS, Chemical communications, (1), 1998, pp. 119-120
Citations number
41
Categorie Soggetti
Chemistry
Journal title
Chemical communications → ACNP
ISSN journal
13597345
Issue
1
Year of publication
1998
Pages
119 - 120
Database
ISI
SICI code
1359-7345(1998):1<119:SOIVHR>2.0.ZU;2-5
Abstract
The alpha-mannosidase inhibitor 1,4-dideoxy-1,4-imino-D-mannitol (DIM) as well as amino analogues of DIM and of deoxy-manno-nojirimycin, res pectively, have been prepared using a diastereoselective nitroaldol ad dition as the key step.