Aj. Swerdlow et Ma. Weinstock, DO TANNING LAMPS CAUSE MELANOMA - AN EPIDEMIOLOGIC ASSESSMENT, Journal of the American Academy of Dermatology, 38(1), 1998, pp. 89-98
Sun exposure is a known cause of melanoma, and there are several reaso
ns for concern that tanning lamp use may also cause melanoma, especial
ly because of the spectral output of the lamps,the similarity of tanni
ng lamp use to natural sun exposure (particularly sunbathing), the rep
orted association of melanoma with PUVA therapy, and the positive resu
lts in several case-control studies of melanoma risk and tanning lamp
use. We have reviewed the epidemiologic literature relevant to the rel
ation between tanning lamp use and melanoma and have discussed methodo
logic issues that should be considered in interpreting these reports a
nd designing improved studies. Although several investigations have fo
und a positive relation between tanning lamp use and melanoma, in some
instances including dose-response or duration-response effects, the m
ethodologic limitations preclude any firm conclusion regarding a causa
tive relation. Meta-analysis of existing data may provide better infor
mation, but several limitations could only be overcome by new studies
collecting more precise exposure data. The popularity of tanning lamp
use, especially in young persons, adds urgency to the quest for elucid
ation of the relation between the use of these devices and melanoma ri
sk.