BIOACTIVE VERSATILE AZOMETHINE COMPLEXES OF ORGANOTIN(IV) AND ORGANOSILICON(IV)

Diorganotin(IV) and diorganosilicon(TV) derivatives of the types R2MCl (TSCZ) and R2M(TSCZ)(2) (where TSCZ is the anion of a thiosemicarbazon e ligand, R=Ph or Me and M=Sn or Si) have been synthesized and charact erized by elemental analyses, molecular weight determinations and cond uctivity measurements, The mode of bonding has been established on the basis of IR and H-1,C-13 Si-29 and Sn-119 NMR spectroscopic studies, Some of the representative complexes have also been evaluated for thei r antimicrobial effects on different species of pathogenic fungi and b acteria in vivo as well as ill vitro, The results of these investigati ons are reported. (C) 1998 John Wiley & Sons, Ltd.