TOTAL SYNTHESIS OF NPTX-643, A NEUROTOXIN OF THE MADAGASCAR SPIDER (NEPHILENGYS BORBONICA) HAVING A NOVEL ACYLPOLYAMINE STRUCTURE

Authors
MIYASHITA M KANEMURA T MATSUSHITA M HATAKEYAMA S ITAGAKI Y NAKAJIMA T MIYAZAWA M IRIE H
Citation
M. Miyashita et al., TOTAL SYNTHESIS OF NPTX-643, A NEUROTOXIN OF THE MADAGASCAR SPIDER (NEPHILENGYS BORBONICA) HAVING A NOVEL ACYLPOLYAMINE STRUCTURE, Heterocycles, 47(1), 1998, pp. 171-175
Citations number
25
Categorie Soggetti
Chemistry Inorganic & Nuclear
Journal title
Heterocycles → ACNP
ISSN journal
03855414
Volume
47
Issue
1
Year of publication
1998
Pages
171 - 175
Database
ISI
SICI code
0385-5414(1998)47:1<171:TSONAN>2.0.ZU;2-P
Abstract
The first total synthesis of NPTX-643, a neurotoxin of the Madagascar spider (Nephilengys borbonica) having a unique cadaverine - nor-putrea nine - putreanine acylpolyamine chain, has been achieved by using thre e key azide intermediates.