MITSUNOBU TYPE C-N BOND FORMATION WITH ETHYL-3,5,7-HEXAHYDRO-1,2,4,7-TETRAZOCIN-3,8-DIONE (DHTD), A NEW CYCLIC AZODICARBOXAMIDE

Authors
TSUNODA T KAWAMURA Y UEMOTO K ITO S
Citation
T. Tsunoda et al., MITSUNOBU TYPE C-N BOND FORMATION WITH ETHYL-3,5,7-HEXAHYDRO-1,2,4,7-TETRAZOCIN-3,8-DIONE (DHTD), A NEW CYCLIC AZODICARBOXAMIDE, Heterocycles, 47(1), 1998, pp. 177-179
Citations number
12
Categorie Soggetti
Chemistry Inorganic & Nuclear
Journal title
Heterocycles → ACNP
ISSN journal
03855414
Volume
47
Issue
1
Year of publication
1998
Pages
177 - 179
Database
ISI
SICI code
0385-5414(1998)47:1<177:MTCBFW>2.0.ZU;2-2
Abstract
The combination of ethyl-3,5,7-hexahydro-1,2,4,7-tetrazocin-3,8-dione (DHTD) and tributylphosphine (TBP) was found to mediate successfully C -N bond formation between N-methyltosylamide, a typical N-nucleophile, and several alcohols of different structural types. The unique featur e of this combination is that it activates the reaction of sec-alcohol s at room temperature.