SPECTRAL PROPERTIES OF BISBENZIMIDAZOLE D YES UPON INTERACTION WITH DNA

Absorption and fluorescence spectra of a series of bisbenzimidazole dy es were studied in the presence of various concentrations of DNA and i n diverse media. Variations in spectral properties of the compounds un der study were found to depend on the measurement conditions. The base s for selecting the optimal composition of the media for DNA detection were presented. The modes of substrate-ligand binding and the dynamic s of the alterations of fluorescent properties of structurally varying dyes upon their interaction with DNA were considered.