E. Chryssanthou et al., COMPARISON OF BROTH MACRODILUTION, BROTH MICRODILUTION AND E-TEST SUSCEPTIBILITY TESTS OF CRYPTOCOCCUS-NEOFORMANS FOR FLUCONAZOLE, Mycoses, 40(11-12), 1997, pp. 423-427
Forty Cryptococcus neoformans strains isolated from cerebral spinal fl
uid specimens collected from 39 patients were included in the study. T
he MICs for fluconacole were determined by YNB macrodilution test, mic
rodilution tests using both RPMI1640 and YNB medium and E-tests on sol
idified RPMI1640 medium, Casitone and YNB agar. In comparison with the
reference macrodilution method NCCLS M27-P both the microdilution as
well as the E-test techniques can be used for fluconacole susceptibili
ty testing of Cr. neoformans.