COMPARATIVE MOLECULAR-FIELD ANALYSIS (COMFA) OF NEW HERBICIDAL SULFONYLUREA COMPOUNDS

Authors
LIU J LI ZM WANG X MA Y LAI CM JIA GF WANG LX
Citation
J. Liu et al., COMPARATIVE MOLECULAR-FIELD ANALYSIS (COMFA) OF NEW HERBICIDAL SULFONYLUREA COMPOUNDS, Science in China. Series B, Chemistry, life sciences & earth sciences, 41(1), 1998, pp. 50-53
Citations number
7
Categorie Soggetti
Chemistry
Journal title
Science in China. Series B, Chemistry, life sciences & earth sciences → ACNP
ISSN journal
1001652X
Volume
41
Issue
1
Year of publication
1998
Pages
50 - 53
Database
ISI
SICI code
1001-652X(1998)41:1<50:CMA(ON>2.0.ZU;2-K
Abstract
A series of new herbicidal sulfonylurea compounds were investigated ai ming at developing a three-dimensional quantitative structure-activity relationship (3D-QSAR) model using the CoMFA technique. On this base, some molecular structures were modified to improve their activities. A model of the target acetolactate syntheses (ALS) enzyme was establis hed for the first time, which is useful to design and synthesis of new ALS enzyme inhibitor.