ASSIGNMENT OF 3 CHINESE XERODERMA-PIGMENTOSUM PATIENTS TO COMPLEMENTATION GROUP-C AND ONE TO GROUP-E

Four Chinese patients with xeroderma pigmentosum (XP), who had differe nt degrees of skin symptoms, were tested for their genetic complementa tion groups. Skin fibroblasts obtained from the patients were used for complementation analysis done by a cell-fusion technique. Three of th e patients belonged to group C and one, who had the mildest cutaneous manifestations, to group E. This is the first report of a group E XP p atient in China. Our present findings together with previous reports s uggest that group C XP is more common in China, similar to the distrib ution among Caucasian XP patients but markedly different from the Japa nese distribution.