The authors report the case of a 67-year old man, with no particular m
edical history, presenting a large swelling of the left thigh. Investi
gations conclude to metastases located in muscles of the left thigh an
d of the pelvis, secondary to an adenocarcinoma of presumed pancreatic
origin. With reference to this case, features of muscular metastases
are reviewed. Muscular metastases seldom occur during the course of a
cancer and are exceptionally the first manifestation of a neoplastic p
rocess. They are usually described as a painful mass, but symptoms can
be misleading and delay diagnosis. Images obtained by ultrasonography
, tomodensitometry and magnetic resonance imaging are not specific and
histological examination is necessary to confirm the diagnosis.