Today, prescribers need to distinguish between the clinical practices
based on randomized clinical trialing information and those based on a
nimal physiological data or theory. Now the information on therapeutic
s is becoming more dense, more complex and less available to the clini
cians. Information sources are numerous and varied including data whos
e quality differs. These data are unhierarchised in terms of methodolo
gical quality and clinical relevance. It will be optimal if each presc
riber could himself collect and analyse scientific information. In fac
t this situation cannot be effective in private physician's practices.
An international collaboration, the Cochrane Collaboration, including
volunteers, university researchers, and clinical investigators has th
e following objective: to prepare, maintain and disseminate systematic
reviews of the effects of health care. The Cochrane Collaboration is
thus the most adapted intermediairy between scientifically actualized
data and clinical practitioners.