OBJECTIVE. This study was done to show the potential of using three-di
mensional (3D) sonography to reveal fetal facial anomalies. SUBJECTS A
ND METHODS, Ninety-four healthy fetuses from 15 to 40 weeks' gestation
were studied with a specially developed 3.5-MHz abdominal 3D transduc
er. This imaging system provided conventional two-dimensional (2D) son
ographic images and also generated within seconds high-quality 3D imag
es in the surface and transparent modes with no need for an external w
orkstation. RESULTS, Using this imaging system, we obtained 2D and 3D
images of fetal faces (forehead, eyes, nose, lips, and chin) at six ge
stational ages. At less than 24 weeks' gestation, 65% of facial struct
ures were visualized. The image quality was slightly degraded because
of the small fetal size. At or after 24 weeks' gestation, 84% of facia
l structures were revealed. We found no significant difference in imag
e quality of the fetal face between 2D and 3D sonography. CONCLUSION.
The new 3D sonographic technology can generate within seconds high-qua
lity 3D images of the fetal face. The 3D technology seems to perform a
t least as well as conventional 2D sonography. Our results suggest tha
t 3D sonography has the potential to supplement 2D sonography and migh
t be useful in identifying malformations of the fetal face and chromos
omal abnormalities in utero.