Jf. Hines et al., PROSPECTS FOR HUMAN-PAPILLOMAVIRUS VACCINE DEVELOPMENT - EMERGING HPVVACCINES, Current opinion in infectious diseases, 11(1), 1998, pp. 57-61
This review concentrates on recent advances in human papillomavirus va
ccine development. Strategies for prophylactic HPV subunit vaccines ut
ilizing recombinantly synthesized, immunogenic virus-like particles ar
e discussed. Therapeutic strategies focusing on the induction of cell-
mediated immunity and gene manipulation for the treatment of establish
ed HPV-associated disease are also reviewed. (C) 1998 Rapid Science Lt
d.