Coupled-column liquid and gas chromatography (LC-GC) provides interfac
es that allow the injection of large solvent volumes in capillary GC,
These large-volume injections provide new ways to integrate sample pre
paration into the chromatographic procedure, The combination of on-lin
e extractors, contemporary LC injection devices, reactors, and solid-p
hase extraction cartridges with large-volume injection techniques offe
rs great advantages in the automation of conventional analytical proce
dures.