SUCCESSFUL TREATMENT OF SUPRAVENTRICULAR TACHYCARDIA WITH FLECAINIDE ACETATE - A CASE-REPORT

Citation
K. Amano et al., SUCCESSFUL TREATMENT OF SUPRAVENTRICULAR TACHYCARDIA WITH FLECAINIDE ACETATE - A CASE-REPORT, Fetal diagnosis and therapy, 12(6), 1997, pp. 328-331
Citations number
6
Journal title
ISSN journal
10153837
Volume
12
Issue
6
Year of publication
1997
Pages
328 - 331
Database
ISI
SICI code
1015-3837(1997)12:6<328:STOSTW>2.0.ZU;2-P
Abstract
Background: Efficacy of flecainide acetate for the treatment of fetal supraventricular tachycardia with cardiac failure was reported. Case: For a case in which maternal digoxin therapy failed, flecainide acetat e (400 mg/day) is used from 27 weeks. Cardioversion with improved card iac function occurred 6 days after treatment. Fetal serum flecainide a cetate level was 292 ng/ml which was 64% of the maternal level (453 ng /ml). No adverse maternal side effects were noted with 11 weeks of the rapy. A vigorous male baby, weighing 3,610 g, Apgar 8/9, Ua-pH 7.24, w as born. He is now 1 year of age and in good condition with medication of 5 mg/kg flecainide acetate. Conclusion: Flecainide acetate seemed to be safe for bath mother and fetus, and effective for the treatment of fetal supraventricular tachycardia which is refractory to transplac ental digoxin therapy.