EVALUATION OF PHOSPHOLIPASE-ACTIVITY OF CANDIDA-ALBICANS AND ITS CORRELATION WITH PATHOGENICITY IN MICE

Authors
KOTHAVADE RJ PANTHAKI MH
Citation
Rj. Kothavade et Mh. Panthaki, EVALUATION OF PHOSPHOLIPASE-ACTIVITY OF CANDIDA-ALBICANS AND ITS CORRELATION WITH PATHOGENICITY IN MICE, Journal of Medical Microbiology, 47(2), 1998, pp. 99-102
Citations number
15
Categorie Soggetti
Microbiology
Journal title
Journal of Medical Microbiology → ACNP
ISSN journal
00222615
Volume
47
Issue
2
Year of publication
1998
Pages
99 - 102
Database
ISI
SICI code
0022-2615(1998)47:2<99:EOPOCA>2.0.ZU;2-D
Abstract
Sixty-one isolates of Candida albicans were tested for their phospholi pase activity and this parameter was correlated with pathogenicity in albino mice. Of the isolates tested, 57 (93%) showed appreciable phosp holipase activity and of these, 55 (90%) were pathogenic to mice. A si gnificant correlation was found between phospholipase activity and inv olvement of kidneys in animal pathogenicity studies. The isolates of C . albicans, that exhibited higher phospholipase activity were found to be pathogenic for mice.