Hepatic lesions were analyzed in 33 patients with HIV-infection. The p
atients were divided into two groups by the disease stage: early (stag
e IIB, IIIA, n = 12) and late (stage IIIB and IIIC, n = 21). Markers o
f hepatitis A, B and C were found in 42.4% of patients. Patients of gr
oup 1 had acute and chronic viral hepatitides (75%), hepatic alcoholic
damage. Patients of group 2 developed combined hepatic lesions result
ant from generalized bacterial, fungal and parasitic infections (66.7%
), chronic hepatitides and viral cirrhoses (33.3%), alcohol abuse (33.
3%). Elevated levels of the enzymes (AsAT, AlAT, LDG) at early stages
of HIV-infection were brought about by hepatic involvement while at la
te stages by polyorganic abnormalities.