LATE DIAGNOSIS OF SYSTEMIC LUPUS-ERYTHEMA TOSUS (SLE) WITH ANTIPHOSPHOLIPID SYNDROME

A case of SLE is reported in a 43-year-old female who had initial sign s of the disease 10 years before (exudative pleuritis). SLE ran chroni cally with spontaneous remissions. Insolation in 1985 provoked exacerb ation and further progress. The progression was accompanied with appea rance of antiphospholipid syndrome (APS): habitual miscarriage, livedo , Raunald's syndrome, recurrent thrombophlebitis. Aortic valve disease was more likely to be consequent to non-infectious endocarditis while arterial hypertension as well as proteinuria could be caused by renal thromboangiopathy. This case demonstrates not only a wide spectrum of SLE and APS symptoms but also difficulties which may be faced in the choice of the treatment policy.