PREVENTION OF REPRODUCTIVE DISORDERS INDU CED BY CHEMOTHERAPY IN FEMALES WITH HODGKINS-DISEASE

Authors
IGNASHINA EV PIVNIK AV SHILIN DE NASIBOV OM MARGOLIN OV PUSTOVOIT LA
Citation
Ev. Ignashina et al., PREVENTION OF REPRODUCTIVE DISORDERS INDU CED BY CHEMOTHERAPY IN FEMALES WITH HODGKINS-DISEASE, Terapevticeskij arhiv, 69(11), 1997, pp. 71-73
Citations number
9
Journal title
Terapevticeskij arhiv → ACNP
ISSN journal
00403660
Volume
69
Issue
11
Year of publication
1997
Pages
71 - 73
Database
ISI
SICI code
0040-3660(1997)69:11<71:PORDIC>2.0.ZU;2-V
Abstract
A menstrual function was studied in 24 females treated by drugs for ad vanced stages of Hodgkin's disease. 17 of them received oral contracep tives for preventing gonadotoxic effect of cytostatic agents (the stud y group). 7 women did not use contraceptives (the control group). Afte r chemotherapy menstrual cycle was normal in 88.2% of patients of the study group, whereas in 71.4% of controls artificial menopause develop ed. Oral contraceptives can be recommended to protect the ovaries in t he course of chemotherapy.