The authors have conducted an epidemiological study for multiple myelo
ma morbidity and mortality among 80000 patients of the Medical Center
examined in 1988-1995. Myeloma was diagnosed in 65 cases. Standard inc
idence rate was 4.09, 3.18, and 3.5 per 100000 for myeloma in males, f
emales and both sexes, respectively. Standard mortality was 2.76 and 1
.73 per 100000 for males and females, respectively. The above rates do
not differ much from those of other countries. In terminal myeloma re
nal insufficiency occurred in 39 of 41 cases. In 8 cases chronic pyelo
nephritis was an independent course of renal failure thus indicating t
he importance of its persistent treatment.