ENANTIOSELECTIVITY IN CHIRAL CAPILLARY ELECTROPHORESIS WITH POLYSACCHARIDES

This review surveys enantiomer separation by capillary electrophoresis (CE) using polysaccharides as chiral selectors. Many ionic or electri cally neutral polysaccharides, such as heparin, chondroitin sulfate, d extrin, etc., have been employed successfully for the CE separation of enantiomers. The operational conditions that affect the enantioselect ivity of the chiral separation system will be described. The mechanism of enantioseparation will also be discussed briefly. (C) 1997 Elsevie r Science B.V.