According to history, the population of the British Isles derives its
genepool from a succession of invaders and immigrants. The settlement
pattern of these invaders gave rise to a patchwork of genepools, shown
in previous genetic surveys. Specimens from 1117 blood donors of regi
onally subdivided East Midlands (Derbyshire, Nottinghamshire and Leice
stershire) were analysed for 18 conventional genetic systems (blood gr
oups, serum proteins and red cell enzymes), according to place of resi
dence. Significant differences exist among the five geographically def
ined sub-populations, and it is argued that these are derived From the
historical settlement of continental European populations in the regi
on, especially the Danes and the Vikings.