CATALYTIC GENERATION AND TRAPPING OF ACYLMETALS CONTAINING NI AND CU WITH ENOLATES

Carbonylative cyclization of iodoarenes and iodoalkenes containing a p roximal enolate precursor can selectively provide either cyclic ketone s or lactones in the presence of Ni or Cu catalysts via trapping of pu tative acylmetal derivatives with C-or O-enolates, respectively; the r ing size and regioselectivity of the reaction may be predicted based o n two generalizations derived from the recently developed correspondin g Pd-catalyzed reaction. (C) 1998 Elsevier Science Ltd. All rights res erved.