REGIOSELECTIVE LIPASE-CATALYZED ACYLATION OF 4,6-O-BENZYLIDENE-BETA-D-PYRANOSIDE DERIVATIVES DISPLAYING A RANGE OF ANOMERIC SUBSTITUENTS

Authors
GRIDLEY JJ HACKING AJ OSBORN HMI SPACKMAN DG
Citation
Jj. Gridley et al., REGIOSELECTIVE LIPASE-CATALYZED ACYLATION OF 4,6-O-BENZYLIDENE-BETA-D-PYRANOSIDE DERIVATIVES DISPLAYING A RANGE OF ANOMERIC SUBSTITUENTS, Synlett, (12), 1997, pp. 1397-1399
Citations number
16
Journal title
Synlett → ACNP
ISSN journal
09365214
Issue
12
Year of publication
1997
Pages
1397 - 1399
Database
ISI
SICI code
0936-5214(1997):12<1397:RLAO4>2.0.ZU;2-F
Abstract
The application of lipase enzymes to effect regioselective C-3-O-acyla tion of 4,6-O-benzylidene-beta-D-gluco- and galactopyranosides display ing a range of anomeric substituents is reported. In particular this m ethod has allowed introduction of a variety of acyl protecting groups at the C-3 hydroxyl group of ethyl 4,6-O-benzylidene-1-thio-beta-D-glu copyranoside 9.