SYNTHESIS OF A PHENOLIC ANALOG OF APHIDICOLIN - DIMINISHED STEREOSELECTION IN INTRAMOLECULAR 6-EXO HECK REACTIONS OF SUBSTRATES HAVING A HYDROCARBON TETHER

Authors
ABELMAN MM KADO N OVERMAN LE SARKAR AK
Citation
Mm. Abelman et al., SYNTHESIS OF A PHENOLIC ANALOG OF APHIDICOLIN - DIMINISHED STEREOSELECTION IN INTRAMOLECULAR 6-EXO HECK REACTIONS OF SUBSTRATES HAVING A HYDROCARBON TETHER, Synlett, (12), 1997, pp. 1469-1471
Citations number
13
Journal title
Synlett → ACNP
ISSN journal
09365214
Issue
12
Year of publication
1997
Pages
1469 - 1471
Database
ISI
SICI code
0936-5214(1997):12<1469:SOAPAO>2.0.ZU;2-W
Abstract
Spirotetracycle 14, generated by intramolecular Heck cyclization of 13 , was converted to the phenolic analog 20 of aphidicolin. That the nat ure of the tether connecting insertion partners can dramatically alter diastereoselection in intramolecular Heck reactions is also demonstra ted.