PSEUDOTUMORAL ILEAL NODULAR LYMPHOID HYPE RPLASIA

We report a case of pseudotumoral nodular lymphoid hyperplasia of the ileum in an immunocompetent 62-year-old woman. Ileoscopy showed multip le voluminous, soft, pliable, polypoid ileal lesions. Perendoscopic bi opsies revealed a florid inflammation of the mucosa, characterised by numerous enlarged follicles with well-developed reactive germinal cent res separated by mixed infiltrate of lymphocytes, plasma cells and eos inophils. Immunohistochemistry showed a polytypic staining for kappa a nd lambda light-chains in the follicles and between and confirmed the reactive nature of the infiltrate. CT semi of the abdomen disclosed la rge periileal lymph nodes and a right ileocolectomy was performed. Twe lve cases of pseudotumoral nodular lymphoid hyperplasia of the ileum h ave been reported in the literature in patients older than 25. In all cases, the diagnosis was performed after laparotomy As shown in our ca se report, the diagnosis is possible on multiple perendoscopic biopsie s.