PHENYTOIN TOXICITY IN AN OLDER PATIENT WITH SLOW METABOLISM AND ATYPICAL PRESENTATION

Authors
PITNER JK LONG LD MEYER RP PENNYPACKER LC
Citation
Jk. Pitner et al., PHENYTOIN TOXICITY IN AN OLDER PATIENT WITH SLOW METABOLISM AND ATYPICAL PRESENTATION, Pharmacotherapy, 18(1), 1998, pp. 218-225
Citations number
35
Categorie Soggetti
Pharmacology & Pharmacy
Journal title
Pharmacotherapy → ACNP
ISSN journal
02770008
Volume
18
Issue
1
Year of publication
1998
Pages
218 - 225
Database
ISI
SICI code
0277-0008(1998)18:1<218:PTIAOP>2.0.ZU;2-B
Abstract
Phenytoin toxicity occurred in an older man who received a dosage of 3 00 mg/day. The patient developed high serum phenytoin concentrations f rom this common adult dosage, with symptoms of functional decline and altered mental status. These behaviors were perceived as sun-downing a nd were treated with haloperidol. A long hospitalization was required.