Rc. Martin et al., DEVELOPMENT OF HIGH-ACTIVITY CF-252 SOURCES FOR NEUTRON BRACHYTHERAPY, Applied radiation and isotopes, 48(10-12), 1997, pp. 1567-1570
Citations number
6
Categorie Soggetti
Nuclear Sciences & Tecnology","Radiology,Nuclear Medicine & Medical Imaging","Chemistry Inorganic & Nuclear
The Gershenson Radiation Oncology Center of Wayne State University (WS
U), Detroit, Michigan, is using Cf-252 medical sources for neutron bra
chytherapy. These sources are based on a 20-year-old design containing
less than or equal to 30 mu g Cf-252 in the form of a cermet wire of
Cf2O3 in a palladium matrix. The Radiochemical Engineering Development
Center (REDC) of Oak Ridge National Laboratory has been asked to deve
lop very compact, high-activity Cf-252 neutron Sources for use with re
mote afterloading equipment in order to reduce treatment times and dos
e to clinical personnel and to expedite treatment of brain and other t
umors, To date, the REDC has demonstrated that Cf-252 loadings can be
greatly increased in cermet wires and with much smaller diameters. Equ
ipment designed for hot cell fabrication of these wires is being teste
d. A parallel program is under way to relicense the existing source de
sign for fabrication at the REDC. Published by Elsevier Science Ltd.